NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Acetone

CAS
67-64-1

(CH3)2CO

RTECS
AL3150000
Synonyms & Trade Names

Dimethyl ketone, Ketone propane, 2-Propanone
DOT ID & Guide
1090 / 127

Exposure
Limits

NIOSH REL: TWA 250 ppm (590 mg/m3)
OSHA PEL: TWA 1000 ppm (2400 mg/m3)
IDLH
2500 ppm [10%LEL] See: 67641
Conversion
1 ppm = 2.38 mg/m3
Physical Description
Colorless liquid with a fragrant, mint-like odor.
MW: 58.1
BP: 133°F
FRZ: -140°F
Sol: Miscible
VP: 180 mmHg
IP: 9.69 eV

Sp.Gr: 0.79
Fl.P: 0°F
UEL: 12.8%
LEL: 2.5%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities

Oxidizers, acids
Measurement Methods
NIOSH 1300, 2555, 3800; OSHA 69
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 2500 ppm:
(APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)*
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 10) Any supplied-air respirator*
(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, nose, throat; headache, dizziness, central nervous system depression; dermatitis
Target Organs
Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0087   See MEDICAL TESTS: 0002