NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Acrylamide

CAS
79-06-1

CH2=CHCONH2

RTECS
AS3325000
Synonyms & Trade Names

Acrylamide monomer, Acrylic amide, Propenamide, 2-Propenamide
DOT ID & Guide
2074 / 153P

Exposure
Limits

NIOSH REL: Ca TWA 0.03 mg/m3 [skin] See Appendix A
OSHA PEL: TWA 0.3 mg/m3 [skin]
IDLH
Ca [60 mg/m3] See: 79061
Conversion
Physical Description
White crystalline, odorless solid.
MW: 71.1
BP: 347-572°F (Decomposes)
MLT: 184°F
Sol(86°F): 216%
VP: 0.007 mmHg
IP: 9.50 eV

Sp.Gr: 1.12
Fl.P: 280°F
UEL: ?
LEL: ?

Combustible Solid (may also be dissolved in flammable liquids).
Incompatibilities & Reactivities

Strong oxidizers [Note: May polymerize violently upon melting.]
Measurement Methods
OSHA 21, PV2004
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin; ataxia, numb limbs, paresthesia; muscle weakness; absent deep tendon reflex; hand sweating; lassitude (weakness, exhaustion), drowsiness; reproductive effects; [potential occupational carcinogen]
Target Organs
Eyes, skin, central nervous system, peripheral nervous system, reproductive system

Cancer Site
[in animals: tumors of the lungs, testes, thyroid & adrenal glands]
See also: INTRODUCTION   See ICSC CARD: 0091   See MEDICAL TESTS: 0007