NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005




Synonyms & Trade Names

Acrylonitrile monomer, AN, Cyanoethylene, Propenenitrile, 2-Propenenitrile, VCN, Vinyl cyanide
DOT ID & Guide
1093 / 131P (inhibited)


NIOSH REL: Ca TWA 1 ppm C 10 ppm [15-minute] [skin] See Appendix A
OSHA PEL: [1910.1045] TWA 2 ppm C 10 ppm [15-minute] [skin]
Ca [85 ppm] See: 107131
1 ppm = 2.17 mg/m3
Physical Description
Colorless to pale-yellow liquid with an unpleasant odor. [Note: Odor can only be detected above the PEL.]
MW: 53.1
BP: 171°F
FRZ: -116°F
Sol: 7%
VP: 83 mmHg
IP: 10.91 eV

Sp.Gr: 0.81
Fl.P: 30°F
UEL: 17%
LEL: 3.0%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities

Strong oxidizers, acids & alkalis; bromine; amines [Note: Unless inhibited (usually with methylhydroquinone), may polymerize spontaneously or when heated or in presence of strong alkali. Attacks copper.]
Measurement Methods
NIOSH 1604; OSHA 37
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
(See Appendix E) NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Irritation eyes, skin; asphyxia; headache; sneezing; nausea, vomiting; lassitude (weakness, exhaustion), dizziness; skin vesiculation; scaling dermatitis; [potential occupational carcinogen]
Target Organs
Eyes, skin, cardiovascular system, liver, kidneys, central nervous system

Cancer Site
[brain tumors, lung & bowel cancer]
See also: INTRODUCTION   See ICSC CARD: 0092   See MEDICAL TESTS: 0008