NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Adiponitrile

CAS
111-69-3

NC(CH2)4CN

RTECS
AV2625000
Synonyms & Trade Names

1,4-Dicyanobutane; Hexanedinitrile; Tetramethylene cyanide
DOT ID & Guide
2205 / 153

Exposure
Limits

NIOSH REL: TWA 4 ppm (18 mg/m3)
OSHA PEL: none
IDLH
N.D. See: IDLH INDEX
Conversion
1 ppm = 4.43 mg/m3
Physical Description
Water-white, practically odorless, oily liquid. [Note: A solid below 34°F. Forms cyanide in the body.]
MW: 108.2
BP: 563°F
FRZ: 34°F
Sol: 4.5%
VP: 0.002 mmHg
IP: ?

Sp.Gr: 0.97
Fl.P(oc): 199°F
UEL: 5.0%
LEL: 1.7%

Class IIIA Combustible Liquid: Fl.P. at or above 140F and below 200F.
Incompatibilities & Reactivities

Oxidizers (e.g., perchlorates, nitrates), strong acids (e.g., sulfuric acid) [Note: Decomposes above 194°F, forming hydrogen cyanide.]
Measurement Methods
NIOSH Nitriles Crit. Doc.
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 40 ppm:
(APF = 10) Any supplied-air respirator
Up to 100 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
Up to 200 ppm:
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 250 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, respiratory system; headache, dizziness, lassitude (weakness, exhaustion), confusion, convulsions; blurred vision; dyspnea (breathing difficulty); abdominal pain, nausea, vomiting
Target Organs
Eyes, skin, respiratory system, central nervous system, cardiovascular system
See also: INTRODUCTION   See ICSC CARD: 0211