NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

p-Anisidine

CAS
104-94-9

NH2C6H4OCH3

RTECS
BZ5450000
Synonyms & Trade Names

para-Aminoanisole, 4-Anisidine, p-Methoxyaniline
DOT ID & Guide
2431 / 153

Exposure
Limits

NIOSH REL: TWA 0.5 mg/m3 [skin]
OSHA PEL: TWA 0.5 mg/m3 [skin]
IDLH
50 mg/m3 See: 104949
Conversion
Physical Description
Yellow to brown, crystalline solid with an amine-like odor.
MW: 123.2
BP: 475°F
MLT: 135°F
Sol: Moderate
VP(77°F): 0.006 mmHg
IP: 7.44 eV

Sp.Gr: 1.07
Fl.P: ?
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities

Strong oxidizers
Measurement Methods
NIOSH 2514
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily
Provide: Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 5 mg/m3:
(APF = 10) Any particulate respirator equipped with an N95, R95, or P95 filter (including N95, R95, and P95 filtering facepieces) except quarter-mask respirators. The following filters may also be used: N99, R99, P99, N100, R100, P100. Click here for information on selection of N, R, or P filters.
(APF = 10) Any supplied-air respirator
Up to 12.5 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered air-purifying respirator with a high-efficiency particulate filter.
Up to 25 mg/m3:
(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters.
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and a high-efficiency particulate filter*
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 50 mg/m3:
(APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode*
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Headache, dizziness; cyanosis; red blood cell Heinz bodies
Target Organs
Blood, kidneys, liver, cardiovascular system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0971   See MEDICAL TESTS: 0015