NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

tert-Butyl acetate

CAS
540-88-5

CH3COOC(CH3)3

RTECS
AF7400000
Synonyms & Trade Names

tert-Butyl ester of acetic acid
DOT ID & Guide
1123 / 129

Exposure
Limits

NIOSH REL: TWA 200 ppm (950 mg/m3)
OSHA PEL: TWA 200 ppm (950 mg/m3)
IDLH
1500 ppm [10%LEL] See: 540885
Conversion
1 ppm = 4.75 mg/m3
Physical Description
Colorless liquid with a fruity odor.
MW: 116.2
BP: 208°F
FRZ: ?
Sol: Insoluble
VP: ?
IP: ?

Sp.Gr: 0.87
Fl.P: 72°F
UEL: ?
LEL: 1.5%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities

Nitrates; strong oxidizers, alkalis & acids
Measurement Methods
NIOSH 1450; OSHA 7
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 1500 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions.
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Itch, inflammation eyes; irritation upper respiratory tract; headache; narcosis; dermatitis
Target Organs
respiratory system, eyes, skin, central nervous system
See also: INTRODUCTION