NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

tert-Butyl alcohol

CAS
75-65-0

(CH3)3COH

RTECS
EO1925000
Synonyms & Trade Names

2-Methyl-2-propanol, Trimethyl carbinol
DOT ID & Guide
1120 / 129

Exposure
Limits

NIOSH REL: TWA 100 ppm (300 mg/m3) ST 150 ppm (450 mg/m3)
OSHA PEL: TWA 100 ppm (300 mg/m3)
IDLH
1600 ppm See: 75650
Conversion
1 ppm = 3.03 mg/m3
Physical Description
Colorless solid or liquid (above 77°F) with a camphor-like odor. [Note: Often used in aqueous solutions.]
MW: 74.1
BP: 180°F
FRZ: 78°F
Sol: Miscible
VP(77°F): 42 mmHg
IP: 9.70 eV

Sp.Gr: 0.79 (Solid)
Fl.P: 52°F
UEL: 8.0%
LEL: 2.4%

Combustible Solid Class IB Flammable Liquid
Incompatibilities & Reactivities

Strong mineral acids, strong hydrochloric acid, oxidizers
Measurement Methods
NIOSH 1450; OSHA 7
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 1600 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, nose, throat; drowsiness, narcosis
Target Organs
Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0114