NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

alpha-Chloroacetophenone

CAS
532-27-4

C6H5COCH2Cl

RTECS
AM6300000
Synonyms & Trade Names

2-Chloroacetophenone; Chloromethyl phenyl ketone; Mace®; Phenacyl chloride; Phenyl chloromethyl ketone; Tear gas
DOT ID & Guide
1697 / 153

Exposure
Limits

NIOSH REL: TWA 0.3 mg/m3 (0.05 ppm)
OSHA PEL: TWA 0.3 mg/m3 (0.05 ppm)
IDLH
15 mg/m3 See: 532274
Conversion
1 ppm = 6.32 mg/m3
Physical Description
Colorless to gray crystalline solid with a sharp, irritating odor.
MW: 154.6
BP: 472°F
MLT: 134°F
Sol: Insoluble
VP: 0.005 mmHg
IP: 9.44 eV

Sp.Gr: 1.32
Fl.P: 244°F
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities

Water, steam, strong oxidizers [Note: Slowly corrodes metals.]
Measurement Methods
NIOSH P&CAM291 (II-5)
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 3 mg/m3:
(APF = 10) Any air-purifying half-mask respirator with organic vapor cartridge(s) in combination with an N95, R95, or P95 filter. The following filters may also be used: N99, R99, P99, N100, R100, P100. Click here for information on selection of N, R, or P filters.
(APF = 10) Any supplied-air respirator
Up to 7.5 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered air-purifying respirator with an organic vapor cartridge in combination with a high-efficiency particulate filter.
Up to 15 mg/m3:
(APF = 50) Any air-purifying full-facepiece respirator equipped with organic vapor cartridge(s) in combination with an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters.
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern and having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters.
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure- demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern and having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, respiratory system; pulmonary edema
Target Organs
Eyes, skin, respiratory system
See also: INTRODUCTION   See ICSC CARD: 0128