NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Chlorodifluoromethane

CAS
75-45-6

CHClF2

RTECS
PA6390000
Synonyms & Trade Names

Difluorochloromethane; Fluorocarbon-22; Freon® 22; Genetron® 22; Monochlorodifluoromethane; Refrigerant 22
DOT ID & Guide
1018 / 126

Exposure
Limits

NIOSH REL: TWA 1000 ppm (3500 mg/m3) ST 1250 ppm (4375 mg/m3)
OSHA PEL†: none
IDLH
N.D. See: IDLH INDEX
Conversion
1 ppm = 3.54 mg/m3
Physical Description
Colorless gas with a faint, sweetish odor. [Note: Shipped as a liquefied compressed gas.]
MW: 86.5
BP: -41°F
FRZ: -231°F
Sol(77°F): 0.3%
VP: 9.4 atm
IP: 12.45 eV
RGasD: 3.11

Fl.P: NA
UEL: NA
LEL: NA

Nonflammable Gas
Incompatibilities & Reactivities

Alkalis, alkaline earth metals (e.g., powdered aluminum, sodium, potassium, zinc)
Measurement Methods
NIOSH 1018
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Frostbite
Eyes: Frostbite
Wash skin: No recommendation
Remove: No recommendation
Change: No recommendation
Provide: Frostbite wash
First Aid
(See procedures)
Eye: Frostbite
Skin: Frostbite
Breathing: Respiratory support

Respirator Recommendations
Not available.
Important additional information about respirator selection
Exposure Routes
inhalation, skin and/or eye contact (liquid)
Symptoms
Irritation respiratory system; confusion, drowsiness, ringing in ears; heart palpitations, cardiac arrhythmias; asphyxia; liver, kidney, spleen injury; liquid: frostbite
Target Organs
respiratory system, cardiovascular system, central nervous system, liver, kidneys, spleen
See also: INTRODUCTION   See ICSC CARD: 0049