NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

bis-Chloromethyl ether

CAS
542-88-1

(CH2Cl)2O

RTECS
KN1575000
Synonyms & Trade Names

BCME, bis-CME, Chloromethyl ether, Dichlorodimethyl ether, Dichloromethyl ether, Oxybis(chloromethane)
DOT ID & Guide
2249 / 131

Exposure
Limits

NIOSH REL: Ca See Appendix A
OSHA PEL: [1910.1008] See Appendix B
IDLH
Ca [N.D.] See: IDLH INDEX
Conversion
Physical Description
Colorless liquid with a suffocating odor.
MW: 115.0
BP: 223°F
FRZ: -43°F
Sol: Reacts
VP(72°F): 30 mmHg
IP: ?

Sp.Gr: 1.32
Fl.P: <66°F
UEL: ?
LEL: ?

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities

Acids, water [Note: Reacts with water to form hydrochloric acid & formaldehyde.]
Measurement Methods
OSHA 10
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet (flammable)
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
(See Appendix E) NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, mucous membrane, respiratory system; pulmonary congestion, edema; corneal damage, necrosis; decreased pulmonary function, cough, dyspnea (breathing difficulty), wheezing; blood-stained sputum, bronchial secretions; [potential occupational carcinogen]
Target Organs
Eyes, skin, respiratory system

Cancer Site
[lung cancer]
See also: INTRODUCTION   See ICSC CARD: 0237   See MEDICAL TESTS: 0026