NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Chloromethyl methyl ether



Synonyms & Trade Names

Chlorodimethyl ether, Chloromethoxymethane, CMME, Dimethylchloroether, Methylchloromethyl ether
DOT ID & Guide
1239 / 131


NIOSH REL: Ca See Appendix A
OSHA PEL: [1910.1006] See Appendix B
Physical Description
Colorless liquid with an irritating odor.
MW: 80.5
BP: 138°F
FRZ: -154°F
Sol: Reacts
VP(70°F): 192 mmHg
IP: 10.25 eV

Sp.Gr: 1.06
Fl.P(oc): 32°F
UEL: ?
LEL: ?

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities

Water [Note: Reacts with water to form hydrochloric acid & formaldehyde.]
Measurement Methods
NIOSH P&CAM220 (II-1); OSHA 10
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet (flammable)
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
(See Appendix E) NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Irritation eyes, skin, mucous membrane; pulmonary edema, pulmonary congestion, pneumonitis; skin burns, necrosis; cough, wheezing, pulmonary congestion; blood stained-sputum; weight loss; bronchial secretions; [potential occupational carcinogen]
Target Organs
Eyes, skin, respiratory system

Cancer Site
[in animals: skin & lung cancer]
See also: INTRODUCTION   See ICSC CARD: 0238   See MEDICAL TESTS: 0048