NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Cyclohexanone

CAS
108-94-1

C6H10O

RTECS
GW1050000
Synonyms & Trade Names

Anone, Cyclohexyl ketone, Pimelic ketone
DOT ID & Guide
1915 / 127

Exposure
Limits

NIOSH REL: TWA 25 ppm (100 mg/m3) [skin]
OSHA PEL: TWA 50 ppm (200 mg/m3)
IDLH
700 ppm See: 108941
Conversion
1 ppm = 4.02 mg/m3
Physical Description
Water-white to pale-yellow liquid with a peppermint- or acetone-like odor.
MW: 98.2
BP: 312°F
FRZ: -49°F
Sol: 15%
VP: 5 mmHg
IP: 9.14 eV

Sp.Gr: 0.95
Fl.P: 146°F
UEL: 9.4%
LEL(212°F): 1.1%

Class IIIA Combustible Liquid: Fl.P. at or above 140F and below 200F.
Incompatibilities & Reactivities

Oxidizers, nitric acid
Measurement Methods
NIOSH 1300, 2555; OSHA 1
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 625 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)
Up to 700 ppm:
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure- demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, mucous membrane; headache; narcosis, coma; dermatitis; in animals: liver, kidney damage
Target Organs
Eyes, skin, respiratory system, central nervous system, liver, kidneys
See also: INTRODUCTION   See ICSC CARD: 0425   See MEDICAL TESTS: 0063