NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Diisopropylamine

CAS
108-18-9

[(CH3)2CH]2NH

RTECS
IM4025000
Synonyms & Trade Names

DIPA, N-(1-Methylethyl)-2-propanamine
DOT ID & Guide
1158 / 132

Exposure
Limits

NIOSH REL: TWA 5 ppm (20 mg/m3) [skin]
OSHA PEL: TWA 5 ppm (20 mg/m3) [skin]
IDLH
200 ppm See: 108189
Conversion
1 ppm = 4.14 mg/m3
Physical Description
Colorless liquid with an ammonia- or fish-like odor.
MW: 101.2
BP: 183°F
FRZ: -141°F
Sol: Miscible
VP: 70 mmHg
IP: 7.73 eV

Sp.Gr: 0.72
Fl.P: 20°F
UEL: 7.1%
LEL: 1.1%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities

Strong oxidizers, strong acids
Measurement Methods
NIOSH S141 (II-4)
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact (>5%)
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash (>5%)
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 125 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)
Up to 200 ppm:
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, respiratory system; nausea, vomiting; headache; visual disturbance
Target Organs
Eyes, skin, respiratory system
See also: INTRODUCTION   See ICSC CARD: 0449