Dimethyl sulfate
|
CAS
77-78-1
|
(CH3)2SO4
|
RTECS
WS8225000
|
Synonyms & Trade Names
Dimethyl ester of sulfuric acid, Dimethylsulfate, Methyl sulfate
|
DOT ID & Guide
1595 / 156
|
Exposure
Limits
|
NIOSH REL: Ca TWA 0.1 ppm (0.5 mg/m3) [skin] See Appendix A
|
|
OSHA PEL†: TWA 1 ppm (5 mg/m3) [skin]
|
IDLH
Ca [7 ppm]
See: 77781
|
Conversion
1 ppm = 5.16 mg/m3
|
Physical Description
Colorless, oily liquid with a faint, onion-like odor.
|
MW: 126.1
|
BP: 370°F (Decomposes)
|
FRZ: -25°F
|
Sol(64°F): 3%
|
VP: 0.1 mmHg
|
IP: ?
|
|
Sp.Gr: 1.33
|
Fl.P: 182°F
|
UEL: ?
|
LEL: ?
|
|
|
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
|
Incompatibilities & Reactivities
Strong oxidizers, ammonia solutions [Note: Decomposes in water to sulfuric acid; corrosive to metals.]
|
Measurement Methods
NIOSH 2524
See: NMAM or OSHA Methods |
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
Provide: Eyewash, Quick drench
|
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
|
Respirator Recommendations
NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
|
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
|
Symptoms
Irritation eyes, nose; headache; dizziness; conjunctivitis; photophobia (abnormal visual intolerance to light); periorbital (situated around the eye) edema; dysphonia, aphonia, dysphagia, productive cough; chest pain; dyspnea (breathing difficulty), cyanosis; vomiting, diarrhea; dysuria; analgesia; fever; proteinuria, hematuria (blood in the urine); eye, skin burns; delirium; [potential occupational carcinogen]
|
Target Organs
Eyes, skin, respiratory system, liver, kidneys, central nervous system
Cancer Site
[in animals: nasal & lung cancer]
|
|
See also: INTRODUCTION
See ICSC CARD: 0148 See MEDICAL TESTS: 0084
|
