NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Ethyl butyl ketone

CAS
106-35-4

CH3CH2CO[CH2]3CH3

RTECS
MJ5250000
Synonyms & Trade Names

Butyl ethyl ketone, 3-Heptanone
DOT ID & Guide
1224 / 127

Exposure
Limits

NIOSH REL: TWA 50 ppm (230 mg/m3)
OSHA PEL: TWA 50 ppm (230 mg/m3)
IDLH
1000 ppm See: 106354
Conversion
1 ppm = 4.67 mg/m3
Physical Description
Colorless liquid with a powerful, fruity odor.
MW: 114.2
BP: 298°F
FRZ: -38°F
Sol: 1%
VP: 4 mmHg
IP: 9.02 eV

Sp.Gr: 0.82
Fl.P(oc): 115°F
UEL: ?
LEL: ?

Class II Combustible Liquid: Fl.P. at or above 100F and below 140F.
Incompatibilities & Reactivities

Oxidizers, acetaldehyde, perchloric acid
Measurement Methods
NIOSH 1301, 2553; OSHA 7
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 500 ppm:
(APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*
(APF = 10) Any supplied-air respirator*
Up to 1000 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode*
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)*
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, mucous membrane; headache, narcosis, coma; dermatitis
Target Organs
Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0889