NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Hexafluoroacetone

CAS
684-16-2

(CF3)2CO

RTECS
UC2450000
Synonyms & Trade Names

Hexafluoro-2-propanone; 1,1,1,3,3,3-Hexafluoro-2-propanone; HFA; Perfluoroacetone
DOT ID & Guide
2420 / 125

Exposure
Limits

NIOSH REL: TWA 0.1 ppm (0.7 mg/m3) [skin]
OSHA PEL: none
IDLH
N.D. See: IDLH INDEX
Conversion
1 ppm = 6.79 mg/m3
Physical Description
Colorless gas with a musty odor. [Note: Shipped as a liquefied compressed gas.]
MW: 166.0
BP: -18°F
FRZ: -188°F
Sol: Reacts
VP: 5.8 atm
IP: 11.81 eV
RGasD: 5.76

Fl.P: NA
UEL: NA
LEL: NA

Nonflammable Gas, but highly reactive with water & other substances, releasing heat.
Incompatibilities & Reactivities

Water, acids [Note: Hygroscopic (i.e., absorbs moisture from the air); reacts with moisture to form a highly acidic sesquihydrate.]
Measurement Methods
None available
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact/Frostbite
Eyes: Prevent eye contact/Frostbite
Wash skin: No recommendation
Remove: No recommendation
Change: No recommendation
Provide: Frostbite wash
First Aid
(See procedures)
Eye: Frostbite
Skin: Frostbite
Breathing: Respiratory support

Respirator Recommendations
Not available.
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, skin and/or eye contact
Symptoms
Irritation eyes, skin, mucous membrane, respiratory system; pulmonary edema; liquid: frostbite; in animals: teratogenic, reproductive effects; kidney injury
Target Organs
Eyes, skin, respiratory system, kidneys, reproductive system
See also: INTRODUCTION   See ICSC CARD: 1057