NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

2-Hexanone

CAS
591-78-6

CH3CO[CH2]3CH3

RTECS
MP1400000
Synonyms & Trade Names

Butyl methyl ketone, MBK, Methyl butyl ketone, Methyl n-butyl ketone
DOT ID & Guide

Exposure
Limits

NIOSH REL: TWA 1 ppm (4 mg/m3)
OSHA PEL: TWA 100 ppm (410 mg/m3)
IDLH
1600 ppm See: 591786
Conversion
1 ppm = 4.10 mg/m3
Physical Description
Colorless liquid with an acetone-like odor.
MW: 100.2
BP: 262°F
FRZ: -71°F
Sol: 2%
VP: 11 mmHg
IP: 9.34 eV

Sp.Gr: 0.81
Fl.P: 77°F
UEL: 8%
LEL: ?

Class IC Flammable Liquid: Fl.P. at or above 73F and below 100F.
Incompatibilities & Reactivities

Strong oxidizers
Measurement Methods
NIOSH 1300, 2555; OSHA PV2031
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 10 ppm:
(APF = 10) Any supplied-air respirator
Up to 25 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
Up to 50 ppm:
(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 1600 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, nose; peripheral neuropathy: lassitude (weakness, exhaustion), paresthesia; dermatitis; headache, drowsiness
Target Organs
Eyes, skin, respiratory system, central nervous system, peripheral nervous system
See also: INTRODUCTION   See ICSC CARD: 0489   See MEDICAL TESTS: 0132