NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Isopropylamine

CAS
75-31-0

(CH3)2CHNH2

RTECS
NT8400000
Synonyms & Trade Names

2-Aminopropane, Monoisopropylamine, 2-Propylamine, sec-Propylamine
DOT ID & Guide
1221 / 132

Exposure
Limits

NIOSH REL: See Appendix D
OSHA PEL: TWA 5 ppm (12 mg/m3)
IDLH
750 ppm See: 75310
Conversion
1 ppm = 2.42 mg/m3
Physical Description
Colorless liquid with an ammonia-like odor. [Note: A gas above 91°F.]
MW: 59.1
BP: 91°F
FRZ: -150°F
Sol: Miscible
VP: 460 mmHg
IP: 8.72 eV

Sp.Gr: 0.69
Fl.P(oc): -35°F
UEL: ?
LEL: ?

Class IA Flammable Liquid: Fl.P. below 73F and BP below 100F.
Incompatibilities & Reactivities

Strong acids, strong oxidizers, aldehydes, ketones, epoxides
Measurement Methods
NIOSH S147 (II-3)
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
OSHA
Up to 125 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with cartridge(s) providing protection against the compound of concern
Up to 250 ppm:
(APF = 50) Any chemical cartridge respirator with a full facepiece and cartridge(s) providing protection against the compound of concern
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and cartridge(s) providing protection against the compound of concern
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 750 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, nose, throat; pulmonary edema; visual disturbance; eye, skin burns; dermatitis
Target Organs
Eyes, skin, respiratory system
See also: INTRODUCTION   See ICSC CARD: 0908