NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Isopropyl glycidyl ether



Synonyms & Trade Names

1,2-Epoxy-3-isopropoxypropane; IGE; Isopropoxymethyl oxirane
DOT ID & Guide


NIOSH REL: C 50 ppm (240 mg/m3) [15-minute]
OSHA PEL: TWA 50 ppm (240 mg/m3)
400 ppm See: 4016142
1 ppm = 4.75 mg/m3
Physical Description
Colorless liquid.
MW: 116.2
BP: 279°F
FRZ: ?
Sol: 19%
VP(77°F): 9 mmHg
IP: ?

Sp.Gr: 0.92
Fl.P: 92°F
UEL: ?
LEL: ?

Class IC Flammable Liquid: Fl.P. at or above 73F and below 100F.
Incompatibilities & Reactivities

Strong oxidizers, strong caustics [Note: May form explosive peroxides upon exposure to air or light.]
Measurement Methods
NIOSH 1620; OSHA 7
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
Up to 400 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Irritation eyes, skin, upper respiratory system; skin sensitization; possible hematopoietic, reproductive effects
Target Organs
Eyes, skin, respiratory system, blood, reproductive system
See also: INTRODUCTION   See ICSC CARD: 0171   See MEDICAL TESTS: 0125