NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Maleic anhydride

CAS
108-31-6

C4H2O3

RTECS
ON3675000
Synonyms & Trade Names

cis-Butenedioic anhydride; 2,5-Furanedione; Maleic acid anhydride; Toxilic anhydride
DOT ID & Guide
2215 / 156

Exposure
Limits

NIOSH REL: TWA 1 mg/m3 (0.25 ppm)
OSHA PEL: TWA 1 mg/m3 (0.25 ppm)
IDLH
10 mg/m3 See: 108316
Conversion
1 ppm = 4.01 mg/m3
Physical Description
Colorless needles, white lumps, or pellets with an irritating, choking odor.
MW: 98.1
BP: 396°F
MLT: 127°F
Sol: Reacts
VP: 0.2 mmHg
IP: 9.90 eV

Sp.Gr: 1.48
Fl.P: 218°F
UEL: 7.1%
LEL: 1.4%

Combustible Solid, but may be difficult to ignite.
Incompatibilities & Reactivities

Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F [Note: Reacts slowly with water (hydrolyzes) to form maleic acid.]
Measurement Methods
NIOSH 3512; OSHA 25, 86
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
Provide: Eyewash
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 10 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation nose, upper respiratory system; conjunctivitis; photophobia (abnormal visual intolerance to light), double vision; bronchial asthma; dermatitis
Target Organs
Eyes, skin, respiratory system
See also: INTRODUCTION   See ICSC CARD: 0799