NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Methoxyflurane

CAS
76-38-0

CHCl2CF2OCH3

RTECS
KN7820000
Synonyms & Trade Names

2,2-Dichloro-1,1-difluoroethyl methyl ether; 2,2-Dichloro-1,1-difluoro-1-methoxyethane; Methoflurane; Methoxyfluorane; Penthrane
DOT ID & Guide

Exposure
Limits

NIOSH REL*: C 2 ppm (13.5 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.]
OSHA PEL: none
IDLH
N.D. See: IDLH INDEX
Conversion
1 ppm = 6.75 mg/m3
Physical Description
Colorless liquid with a fruity odor. [inhalation anesthetic]
MW: 165.0
BP: 220°F
FRZ: -31°F
Sol: Slight
VP: 23 mmHg
IP: ?

Sp.Gr(77°F): 1.42
Fl.P: ?
UEL: ?
LEL(176°F): 7%

Combustible Liquid
Incompatibilities & Reactivities

None reported
Measurement Methods
None available
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: No recommendation
Eyes: Prevent eye contact
Wash skin: No recommendation
Remove: When wet or contaminated
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
Not available.
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes; central nervous system depression, analgesia, anesthesia, convulsions, respiratory depression; liver, kidney injury; in animals: reproductive, teratogenic effects
Target Organs
Eyes, central nervous system, liver, kidneys, reproductive system
See also: INTRODUCTION