NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Methyl (n-amyl) ketone

CAS
110-43-0

CH3CO[CH2]4CH3

RTECS
MJ5075000
Synonyms & Trade Names

Amyl methyl ketone, n-Amyl methyl ketone, 2-Heptanone
DOT ID & Guide
1110 / 127

Exposure
Limits

NIOSH REL: TWA 100 ppm (465 mg/m3)
OSHA PEL: TWA 100 ppm (465 mg/m3)
IDLH
800 ppm See: 110430
Conversion
1 ppm = 4.67 mg/m3
Physical Description
Colorless to white liquid with a banana-like, fruity odor.
MW: 114.2
BP: 305°F
FRZ: -32°F
Sol: 0.4%
VP: 3 mmHg
IP: 9.33 eV

Sp.Gr: 0.81
Fl.P: 102°F
UEL(250°F): 7.9%
LEL(151°F): 1.1%

Class II Combustible Liquid: Fl.P. at or above 100F and below 140F.
Incompatibilities & Reactivities

Strong acids, alkalis & oxidizers [Note: Will attack some forms of plastic.]
Measurement Methods
NIOSH 1301, 2553
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash
Breathing: Fresh air
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 800 ppm:
(APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)*
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 10) Any supplied-air respirator*
(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, mucous membrane; headache; narcosis, coma; dermatitis
Target Organs
Eyes, skin, respiratory system, central nervous system, peripheral nervous system
See also: INTRODUCTION   See ICSC CARD: 0920   See MEDICAL TESTS: 0145