NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Methyl Cellosolve® acetate

CAS
110-49-6

CH3COOCH2CH2OCH3

RTECS
KL5950000
Synonyms & Trade Names

EGMEA, Ethylene glycol monomethyl ether acetate, Glycol monomethyl ether acetate, 2-Methoxyethyl acetate
DOT ID & Guide
1189 / 129

Exposure
Limits

NIOSH REL: TWA 0.1 ppm (0.5 mg/m3) [skin]
OSHA PEL: TWA 25 ppm (120 mg/m3) [skin]
IDLH
200 ppm See: 110496
Conversion
1 ppm = 4.83 mg/m3
Physical Description
Colorless liquid with a mild, ether-like odor.
MW: 118.1
BP: 293°F
FRZ: -85°F
Sol: Miscible
VP: 2 mmHg
IP: ?

Sp.Gr: 1.01
Fl.P: 120°F
UEL: 8.2%
LEL: 1.7%

Class II Combustible Liquid: Fl.P. at or above 100F and below 140F.
Incompatibilities & Reactivities

Nitrates; strong oxidizers, alkalis & acids
Measurement Methods
NIOSH 1451; OSHA 53, 79
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 1 ppm:
(APF = 10) Any supplied-air respirator*
Up to 2.5 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode*
Up to 5 ppm:
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 100 ppm:
(APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode*
Up to 200 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, nose, throat; kidney, brain damage; in animals: narcosis; reproductive, teratogenic effects
Target Organs
Eyes, respiratory system, kidneys, brain, central nervous system, peripheral nervous system, reproductive system, hematopoietic system
See also: INTRODUCTION   See ICSC CARD: 0476