NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

5-Methyl-3-heptanone

CAS
541-85-5

C2H5COCH2CH(CH3)CH2CH3

RTECS
MJ7350000
Synonyms & Trade Names

Amyl ethyl ketone, Ethyl amyl ketone, 3-Methyl-5-heptanone
DOT ID & Guide
2271 / 127

Exposure
Limits

NIOSH REL: TWA 25 ppm (130 mg/m3)
OSHA PEL: TWA 25 ppm (130 mg/m3)
IDLH
100 ppm See: 541855
Conversion
1 ppm = 5.24 mg/m3
Physical Description
Colorless liquid with a pungent odor.
MW: 128.2
BP: 315°F
FRZ: -70°F
Sol: Insoluble
VP: 2 mmHg
IP: ?

Sp.Gr: 0.82
Fl.P: 138°F
UEL: ?
LEL: ?

Class II Combustible Liquid: Fl.P. at or above 100F and below 140F.
Incompatibilities & Reactivities

Strong oxidizers
Measurement Methods
NIOSH 1301, 2553
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 100 ppm:
(APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)*
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 10) Any supplied-air respirator*
(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, mucous membrane; headache; narcosis, coma; dermatitis
Target Organs
Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION   See ICSC CARD: 1391