NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Monomethyl aniline

CAS
100-61-8

C6H5NHCH3

RTECS
BY4550000
Synonyms & Trade Names

MA, (Methylamino)benzene, N-Methyl aniline, Methylphenylamine, N-Phenylmethylamine
DOT ID & Guide
2294 / 153

Exposure
Limits

NIOSH REL: TWA 0.5 ppm (2 mg/m3) [skin]
OSHA PEL: TWA 2 ppm (9 mg/m3) [skin]
IDLH
100 ppm See: 100618
Conversion
1 ppm = 4.38 mg/m3
Physical Description
Yellow to light-brown liquid with a weak, ammonia-like odor.
MW: 107.2
BP: 384°F
FRZ: -71°F
Sol: Insoluble
VP: 0.3 mmHg
IP: 7.32 eV

Sp.Gr: 0.99
Fl.P: 175°F
UEL: ?
LEL: ?

Class IIIA Combustible Liquid: Fl.P. at or above 140F and below 200F.
Incompatibilities & Reactivities

Strong acids, strong oxidizers
Measurement Methods
NIOSH 3511
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 5 ppm:
(APF = 10) Any supplied-air respirator
Up to 12.5 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
Up to 25 ppm:
(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 100 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Lassitude (weakness, exhaustion), dizziness, headache; dyspnea (breathing difficulty), cyanosis; methemoglobinemia; pulmonary edema; liver, kidney damage
Target Organs
respiratory system, liver, kidneys, blood, central nervous system
See also: INTRODUCTION   See ICSC CARD: 0921   See MEDICAL TESTS: 0151