NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

p-Nitroaniline

CAS
100-01-6

NO2C6H4NH2

RTECS
BY7000000
Synonyms & Trade Names

para-Aminonitrobenzene, 4-Nitroaniline, 4-Nitrobenzenamine, p-Nitrophenylamine, PNA
DOT ID & Guide
1661 / 153

Exposure
Limits

NIOSH REL: TWA 3 mg/m3 [skin]
OSHA PEL: TWA 6 mg/m3 (1 ppm) [skin]
IDLH
300 mg/m3 See: 100016
Conversion
Physical Description
Bright yellow, crystalline powder with a slight ammonia-like odor.
MW: 138.1
BP: 630°F
MLT: 295°F
Sol: 0.08%
VP: 0.00002 mmHg
IP: 8.85 eV

Sp.Gr: 1.42
Fl.P: 390°F
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities

Strong oxidizers, strong reducers [Note: May result in spontaneous heating of organic materials in the presence of moisture.]
Measurement Methods
NIOSH 5033
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 30 mg/m3:
(APF = 10) Any supplied-air respirator*
Up to 75 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode*
Up to 150 mg/m3:
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 300 mg/m3:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation nose, throat; cyanosis, ataxia; tachycardia, tachypnea; dyspnea (breathing difficulty); irritability; vomiting, diarrhea; convulsions; respiratory arrest; anemia; methemoglobinemia; jaundice
Target Organs
respiratory system, blood, heart, liver
See also: INTRODUCTION   See ICSC CARD: 0308   See MEDICAL TESTS: 0160