NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

n-Propyl nitrate

CAS
627-13-4

CH3CH2CH2ONO2

RTECS
UK0350000
Synonyms & Trade Names

Propyl ester of nitric acid
DOT ID & Guide
1865 / 131

Exposure
Limits

NIOSH REL: TWA 25 ppm (105 mg/m3) ST 40 ppm (170 mg/m3)
OSHA PEL: TWA 25 ppm (110 mg/m3)
IDLH
500 ppm See: 627134
Conversion
1 ppm = 4.30 mg/m3
Physical Description
Colorless to straw-colored liquid with an ether-like odor.
MW: 105.1
BP: 231°F
FRZ: -148°F
Sol: Slight
VP: 18 mmHg
IP: 11.07 eV

Sp.Gr: 1.07
Fl.P: 68°F
UEL: 100%
LEL: 2%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities

Strong oxidizers, combustible materials [Note: Forms explosive mixtures with combustible materials.]
Measurement Methods
NIOSH S227 (II-3); OSHA 7
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 250 ppm:
(APF = 10) Any supplied-air respirator
Up to 500 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
In animals: irritation eyes, skin; methemoglobinemia, anoxia, cyanosis; dyspnea (breathing difficulty), lassitude (weakness, exhaustion), dizziness, headache
Target Organs
Eyes, skin, blood
See also: INTRODUCTION   See MEDICAL TESTS: 0198