NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Subtilisins

CAS
1395-21-7 (BPN)
9014-01-1 (Carlsburg)


RTECS
CO9450000 (BPN)
CO9550000 (Carlsburg)
Synonyms & Trade Names

Bacillus subtilis, Bacillus subtilis BPN, Bacillus subtilis Carlsburg, Proteolytic enzymes, Subtilisin BPN, Subtilisin Carlsburg [Note: Commercial proteolytic enzymes are used in laundry detergents.]
DOT ID & Guide

Exposure
Limits

NIOSH REL: ST 0.00006 mg/m3 [60-minute]
OSHA PEL: none
IDLH
N.D. See: IDLH INDEX
Conversion
Physical Description
Light-colored, free-flowing powders. [Note: A protein containing numerous amino acids.]
MW: 28,000 (approx)
BP: ?
MLT: ?
Sol: ?
VP: 0 mmHg (approx)
IP: NA

Sp.Gr: ?
Fl.P: NA
UEL: NA
LEL: NA

Incompatibilities & Reactivities

None reported
Measurement Methods
None available
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
Not available.
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, respiratory system; respiratory sensitization (enzyme asthma): sweating, headache, chest pain, flu-like symptoms, cough, breathlessness, wheezing
Target Organs
Eyes, skin, respiratory system
See also: INTRODUCTION