NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Tetramethyl succinonitrile



Synonyms & Trade Names

Tetramethyl succinodinitrile, TMSN
DOT ID & Guide


NIOSH REL: TWA 3 mg/m3 (0.5 ppm) [skin]
OSHA PEL: TWA 3 mg/m3 (0.5 ppm) [skin]
5 ppm See: 3333526
1 ppm = 5.57 mg/m3
Physical Description
Colorless, odorless solid. [Note: Forms cyanide in the body.]
MW: 136.2
BP: Sublimes
MLT: 338°F (Sublimes)
Sol: Insoluble
VP: ?
IP: ?

Sp.Gr: 1.07
Fl.P: ?
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities

Strong oxidizers
Measurement Methods
NIOSH S155 (II-3); OSHA 7
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
Up to 28 mg/m3:
(APF = 10) Any supplied-air respirator
(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure- demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Headache, nausea; convulsions, coma; liver, kidney, gastrointestinal effects
Target Organs
central nervous system, liver, kidneys, gastrointestinal tract
See also: INTRODUCTION   See ICSC CARD: 1121