NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Trimethylamine

CAS
75-50-3

(CH3)3N

RTECS
PA0350000
Synonyms & Trade Names

N,N-Dimethylmethanamine; TMA [Note: May be used in an aqueous solution (typically 25%, 30%, or 40% TMA.]
DOT ID & Guide
1083 / 118 (anhydrous)
1297 / 132 (aqueous solution)

Exposure
Limits

NIOSH REL: TWA 10 ppm (24 mg/m3) ST 15 ppm (36 mg/m3)
OSHA PEL: none
IDLH
N.D. See: IDLH INDEX
Conversion
1 ppm = 2.42 mg/m3
Physical Description
Colorless gas with a fishy, amine odor. [Note: A liquid below 37°F. Shipped as a liquefied compressed gas.]
MW: 59.1
BP: 37°F
FRZ: -179°F
Sol(86°F): 48%
VP(70°F): 1454 mmHg
IP: 7.82 eV
RGasD: 2.09

Fl.P: NA (Gas) 20°F (Liquid)
UEL: 11.6%
LEL: 2.0%

Flammable Gas
Incompatibilities & Reactivities

Strong oxidizers (including bromine), ethylene oxide, nitrosating agents (e.g., sodium nitrite), mercury, strong acids [Note: Corrosive to many metals (e.g., zinc, brass, aluminum, copper).]
Measurement Methods
OSHA PV2060
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact (liquid/solution)/Frostbite
Eyes: Prevent eye contact (liquid/solution)/Frostbite
Wash skin: When contaminated (solution)
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash (liquid/solution), Quick drench (liquid/solution), Frostbite wash
First Aid
(See procedures)
Eye: Irrigate immediately (liquid/solution)/Frostbite
Skin: Water flush immediately (liquid/solution)/Frostbite
Breathing: Respiratory support
Swallow: Medical attention immediately (solution)
Respirator Recommendations
Not available.
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion (solution), skin and/or eye contact
Symptoms
Irritation eyes, skin, nose, throat, respiratory system; cough, dyspnea (breathing difficulty), delayed pulmonary edema; blurred vision, corneal necrosis; skin burns; liquid: frostbite
Target Organs
Eyes, skin, respiratory system
See also: INTRODUCTION   See ICSC CARD: 0206