NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Xylidine

CAS
1300-73-8

(CH3)2C6H3NH2

RTECS
ZE8575000
Synonyms & Trade Names

Aminodimethylbenzene, Aminoxylene, Dimethylaminobenzene, Dimethylaniline, Xylidine isomers (e.g., 2,4-Dimethylaniline) [Note: Dimethylaniline is also used as a synonym for N,N-Dimethylaniline.]
DOT ID & Guide
1711 / 153

Exposure
Limits

NIOSH REL: TWA 2 ppm (10 mg/m3) [skin]
OSHA PEL: TWA 5 ppm (25 mg/m3) [skin]
IDLH
50 ppm See: 1300738
Conversion
1 ppm = 4.96 mg/m3
Physical Description
Pale-yellow to brown liquid with a weak, aromatic, amine-like odor.
MW: 121.2
BP: 415-439°F
FRZ: -33°F
Sol: Slight
VP: <1 mmHg
IP: 7.65 eV (2,4-) 7.30 eV (2,6-)

Sp.Gr: 0.98
Fl.P: 206°F (2,3-)
UEL: ?
LEL: 1.0% (o-isomer)

Class IIIB Combustible Liquid (2,3-)
Incompatibilities & Reactivities

Strong oxidizers, hypochlorite salts
Measurement Methods
NIOSH 2002
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 20 ppm:
(APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)
(APF = 10) Any supplied-air respirator
Up to 50 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Anoxia, cyanosis, methemoglobinemia; lung, liver, kidney damage
Target Organs
respiratory system, blood, liver, kidneys, cardiovascular system
See also: INTRODUCTION   See ICSC CARD: 0600   See MEDICAL TESTS: 0244