Acetonitrile
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CAS
75-05-8
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CH3CN
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RTECS
AL7700000
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Synonyms & Trade Names
Cyanomethane, Ethyl nitrile, Methyl cyanide [Note: Forms cyanide in the body.]
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DOT ID & Guide
1648 / 127
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Exposure Limits
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NIOSH REL: TWA 20 ppm (34 mg/m3)
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OSHA PEL†: TWA 40 ppm (70 mg/m3)
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IDLH
500 ppm
See: 75058
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Conversion
1 ppm = 1.68 mg/m3
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Physical Description
Colorless liquid with an aromatic odor.
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MW: 41.1
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BP: 179°F
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FRZ: -49°F
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Sol: Miscible
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VP: 73 mmHg
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IP: 12.20 eV
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Sp.Gr: 0.78
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Fl.P(oc): 42°F
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UEL: 16.0%
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LEL: 3.0%
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Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
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Incompatibilities & Reactivities
Strong oxidizers
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Measurement Methods
NIOSH 1606
See: NMAM or OSHA Methods |
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Quick drench
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First Aid (See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
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Respirator Recommendations
NIOSH
Up to 200 ppm: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s) (APF = 10) Any supplied-air respirator
Up to 500 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode (APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s) (APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s) (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister (APF = 50) Any self-contained breathing apparatus with a full facepiece (APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode (APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
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Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
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Symptoms
Irritation nose, throat; asphyxia; nausea, vomiting; chest pain; lassitude (weakness, exhaustion); stupor, convulsions; in animals: liver, kidney damage
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Target Organs
respiratory system, cardiovascular system, central nervous system, liver, kidneys
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See also: INTRODUCTION
See ICSC CARD: 0088 See MEDICAL TESTS: 0003
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