NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Endrin

CAS
72-20-8

C12H8Cl6O

RTECS
IO1575000
Synonyms & Trade Names

1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro- 1,4-endo,endo-5,8-dimethanonaphthalene; Hexadrin®
DOT ID & Guide
2761 / 151

Exposure
Limits

NIOSH REL: TWA 0.1 mg/m3 [skin]
OSHA PEL: TWA 0.1 mg/m3 [skin]
IDLH
2 mg/m3 See: 72208
Conversion
Physical Description
Colorless to tan, crystalline solid with a mild, chemical odor. [insecticide]
MW: 380.9
BP: Decomposes
MLT: 392°F (Decomposes)
Sol: Insoluble
VP: Low
IP: ?

Sp.Gr: 1.70
Fl.P: NA
UEL: NA
LEL: NA

Noncombustible Solid, but may be dissolved in flammable liquids.
Incompatibilities & Reactivities

Strong oxidizers, strong acids, parathion [Note: May emit hydrogen chloride & phosgene when heated or burned.]
Measurement Methods
NIOSH 5519
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 1 mg/m3:
(APF = 10) Any air-purifying half-mask respirator with organic vapor cartridge(s) in combination with an N95, R95, or P95 filter. The following filters may also be used: N99, R99, P99, N100, R100, P100. Click here for information on selection of N, R, or P filters.
(APF = 10) Any supplied-air respirator
Up to 2 mg/m3:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered air-purifying respirator with an organic vapor cartridge in combination with a high-efficiency particulate filter.
(APF = 50) Any air-purifying full-facepiece respirator equipped with organic vapor cartridge(s) in combination with an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters.
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters.
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Epileptiform convulsions; stupor, headache, dizziness; abdominal discomfort, nausea, vomiting; insomnia; aggressiveness, confusion; drowsiness, lassitude (weakness, exhaustion); anorexia; in animals: liver damage
Target Organs
central nervous system, liver
See also: INTRODUCTION   See ICSC CARD: 1023   See MEDICAL TESTS: 0092