Epichlorohydrin
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CAS
106-89-8
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C3H5OCl
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RTECS
TX4900000
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Synonyms & Trade Names
1-Chloro-2,3-epoxypropane; 2-Chloropropylene oxide; gamma-Chloropropylene oxide
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DOT ID & Guide
2023 / 131P
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Exposure
Limits
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NIOSH REL: Ca See Appendix A
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OSHA PEL†: TWA 5 ppm (19 mg/m3) [skin]
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IDLH
Ca [75 ppm]
See: 106898
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Conversion
1 ppm = 3.78 mg/m3
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Physical Description
Colorless liquid with a slightly irritating, chloroform-like odor.
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MW: 92.5
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BP: 242°F
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FRZ: -54°F
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Sol: 7%
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VP: 13 mmHg
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IP: 10.60 eV
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Sp.Gr: 1.18
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Fl.P: 93°F
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UEL: 21.0%
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LEL: 3.8%
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Class IC Flammable Liquid: Fl.P. at or above 73°F and below 100°F.
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Incompatibilities & Reactivities
Strong oxidizers, strong acids, certain salts, caustics, zinc, aluminum, water [Note: May polymerize in presence of strong acids and bases, particularly when hot.]
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Measurement Methods
NIOSH 1010; OSHA 7
See: NMAM or OSHA Methods |
Personal Protection & Sanitation (See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash, Quick drench
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First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
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Respirator Recommendations
NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor and acid gas canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
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Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
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Symptoms
Irritation eyes, skin with deep pain; nausea, vomiting; abdominal pain; respiratory distress, cough; cyanosis; reproductive effects; [potential occupational carcinogen]
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Target Organs
Eyes, skin, respiratory system, kidneys, liver, reproductive system
Cancer Site
[in animals: nasal cancer]
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See also: INTRODUCTION
See ICSC CARD: 0043 See MEDICAL TESTS: 0093
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