NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Glycolonitrile

CAS
107-16-4

HOCH2CN

RTECS
AM0350000
Synonyms & Trade Names

Cyanomethanol, Formaldehyde cyanohydrin, Glycolic nitrile, Glyconitrile, Hydroxyacetonitrile
DOT ID & Guide

Exposure
Limits

NIOSH REL: C 2 ppm (5 mg/m3) [15-minute]
OSHA PEL: none
IDLH
N.D. See: IDLH INDEX
Conversion
1 ppm = 2.34 mg/m3
Physical Description
Colorless, odorless, oily liquid. [Note: Forms cyanide in the body.]
MW: 57.1
BP: 361°F (Decomposes)
FRZ: <-98°F
Sol: Soluble
VP(145°F): 1 mmHg
IP: ?

Sp.Gr(66°F): 1.10
Fl.P: ?
UEL: ?
LEL: ?

Combustible Liquid
Incompatibilities & Reactivities

Traces of alkalis (promote violent polymerization)
Measurement Methods
None available
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
Up to 20 ppm:
(APF = 10) Any supplied-air respirator
Up to 50 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
Up to 100 ppm:
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Up to 250 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, skin, respiratory system; headache, dizziness, lassitude (weakness, exhaustion), confusion, convulsions; dyspnea (breathing difficulty); abdominal pain, nausea, vomiting
Target Organs
Eyes, skin, respiratory system, central nervous system, cardiovascular system
See also: INTRODUCTION