NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Isopropyl alcohol

CAS
67-63-0

(CH3)2CHOH

RTECS
NT8050000
Synonyms & Trade Names

Dimethyl carbinol, IPA, Isopropanol, 2-Propanol, sec-Propyl alcohol, Rubbing alcohol
DOT ID & Guide
1219 / 129

Exposure
Limits

NIOSH REL: TWA 400 ppm (980 mg/m3) ST 500 ppm (1225 mg/m3)
OSHA PEL†: TWA 400 ppm (980 mg/m3)
IDLH
2000 ppm [10%LEL] See: 67630
Conversion
1 ppm = 2.46 mg/m3
Physical Description
Colorless liquid with the odor of rubbing alcohol.
MW: 60.1
BP: 181°F
FRZ: -127°F
Sol: Miscible
VP: 33 mmHg
IP: 10.10 eV

Sp.Gr: 0.79
Fl.P: 53°F
UEL(200°F): 12.7%
LEL: 2.0%

Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Incompatibilities & Reactivities

Strong oxidizers, acetaldehyde, chlorine, ethylene oxide, acids, isocyanates
Measurement Methods
NIOSH 1400; OSHA 109
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH/OSHA
Up to 2000 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode£
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)£
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
Irritation eyes, nose, throat; drowsiness, dizziness, headache; dry cracking skin; in animals: narcosis
Target Organs
Eyes, skin, respiratory system
See also: INTRODUCTION   See ICSC CARD: 0554   See MEDICAL TESTS: 0124