NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

Kepone

CAS
143-50-0

C10Cl10O

RTECS
PC8575000
Synonyms & Trade Names

Chlordecone; Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)-pentalen-2-one; Decachlorooctahydro-kepone-2-one; Decachlorotetrahydro-4,7-methanoindeneone
DOT ID & Guide

Exposure
Limits

NIOSH REL: Ca TWA 0.001 mg/m3 See Appendix A
OSHA PEL: none
IDLH
Ca [N.D.] See: IDLH INDEX
Conversion
Physical Description
Tan to white, crystalline, odorless solid. [insecticide]
MW: 490.6
BP: Sublimes
MLT: 662°F (Sublimes)
Sol(212°F): 0.5%
VP(77°F): 3 x 10-7 mmHg
IP: ?

Sp.Gr: ?
Fl.P: NA
UEL: NA
LEL: NA

Noncombustible Solid
Incompatibilities & Reactivities

Acids, acid fumes
Measurement Methods
NIOSH 5508
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Headache, anxiety, tremor; liver, kidney damage; visual disturbance; ataxia, chest pain, skin erythema (skin redness); testicular atrophy, low sperm count; [potential occupational carcinogen]
Target Organs
Eyes, skin, respiratory system, central nervous system, liver, kidneys, reproductive system

Cancer Site
[in animal: liver cancer]
See also: INTRODUCTION