NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

4-Nitrobiphenyl

CAS
92-93-3

C6H5C6H4NO2

RTECS
DV5600000
Synonyms & Trade Names

p-Nitrobipheny, p-Nitrodiphenyl, 4-Nitrodiphenyl, p-Phenylnitrobenzene, 4-Phenylnitrobenzene, PNB
DOT ID & Guide

Exposure
Limits

NIOSH REL: Ca See Appendix A
OSHA PEL: [1910.1003] See Appendix B
IDLH
Ca [N.D.] See: IDLH INDEX
Conversion
Physical Description
White to yellow, needle-like, crystalline solid with a sweetish odor.
MW: 199.2
BP: 644°F
MLT: 237°F
Sol: Insoluble
VP: ?
IP: ?

Sp.Gr: ?
Fl.P: 290°F
UEL: ?
LEL: ?

Combustible Solid
Incompatibilities & Reactivities

Strong reducers
Measurement Methods
NIOSH P&CAM273 (II-4); OSHA PV2082
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
(See Appendix E) NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Headache, drowsiness, dizziness; dyspnea (breathing difficulty); ataxia, lassitude (weakness, exhaustion); methemoglobinemia; urinary burning; acute hemorrhagic cystitis; [potential occupational carcinogen]
Target Organs
Bladder, blood

Cancer Site
[in animals: bladder tumors]
See also: INTRODUCTION   See ICSC CARD: 1395   See MEDICAL TESTS: 0162