NIOSH Publication No. 2005-151:

NIOSH Pocket Guide to Chemical Hazards

September 2005

N-Nitrosodimethylamine

CAS
62-75-9

(CH3)2N2O

RTECS
IQ0525000
Synonyms & Trade Names

Dimethylnitrosamine; N,N-Dimethylnitrosamine; DMNA; N-Methyl-N-nitroso-methanamine; NDMA; N-Nitroso-N,N-dimethylamine
DOT ID & Guide

Exposure
Limits

NIOSH REL: Ca See Appendix A
OSHA PEL: [1910.1016] See Appendix B
IDLH
Ca [N.D.] See: IDLH INDEX
Conversion
Physical Description
Yellow, oily liquid with a faint, characteristic odor.
MW: 74.1
BP: 306°F
FRZ: ?
Sol: Soluble
VP: 3 mmHg
IP: 8.69 eV

Sp.Gr: 1.005
Fl.P: ?
UEL: ?
LEL: ?

Combustible Liquid
Incompatibilities & Reactivities

Strong oxidizers [Note: Should be stored in dark bottles.]
Measurement Methods
NIOSH 2522; OSHA 38
See: NMAM or OSHA Methods
Personal Protection & Sanitation
(See protection)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations
(See Appendix E) NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape:
(APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters./Any appropriate escape-type, self-contained breathing apparatus
Important additional information about respirator selection
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
Nausea, vomiting, diarrhea, abdominal cramps; headache; fever; enlarged liver, jaundice; decreased liver, kidney, pulmonary function; [potential occupational carcinogen]
Target Organs
Liver, kidneys,lungs

Cancer Site
[in animals; lung, kidney, liver & nasal cavity tumors]
See also: INTRODUCTION   See ICSC CARD: 0525   See MEDICAL TESTS: 0167